Description
Capsid Biology Scientist-Houston, TX
Kelly Science & Clinical is currently seeking a Capsid Biology Scientist for a biopharma/biotech company in near Southwest Houston. The Capsid Biology Scientist will focus on the planning, execution, and analysis of studies targeted to support our client's viral vector platform. The role will focus on developing early stage production process for recombinant AAV vector preparations for improved gene delivery. Job functions will include routine cell expansion, cell screening, identifying conditions best for production of viral vector(s) in small scale that meet quality criteria. Other job functions may include laboratory maintenance, procurement of essential consumables, and cross-collaborative assistance with downstream process development and Pre-clinical groups.
Responsibilities
• Independently perform routine suspension cell culture (sampling, cell counting, passaging)
• Independently maintains and manages upstream lab equipment appropriately
• Independent execution in the preparation of reagents, experimental set up, and data analysis and future study designs
• Support upstream technology strategies by discovering and optimizing next generation AAV capsids production process.; Assist in and execute unit operations for development, viral vector production process.
• Contributes to continuous improvement strategies by designing experiments and presentation of results to internal and external stakeholders; stay up to date with advancements in AAV biology
• Ensuring adequate and appropriate inventory of materials and supplies, collaboration with supply chain, ordering materials
• Draft, edit, and/or review data capture forms, batch production records, standard operating procedures or standard work elements for process development equipment and/or unit operations.
• Maintain responsible laboratory protocols, data capture, lab notebooks, and/or files using GDP
• Collaborates with pre-clinical and analytical development, on the planning of upstream process development project timelines
Qualifications
Masters in a Biological Science/ Virology
Required Skills
• Expertise in capsid biology for AAV gene therapy vectors
• Handling various sized shake flasks for suspension cell culture in a process development setting
• Experience in and understanding of operations within a biosafety cabinet, cell culture incubators, cell culture shaking platforms, centrifugation equipment, aseptic technique, and associated general cleaning procedures
• Experience with media preparations, monitoring cell culture, routine sampling, preparation, execution, and analysis of cell expansion
• Experience using MS Office, Excel and basic cell kinetic analysis
Preferred Skills
• Experience in protein engineering is a plus
• AAV bioprocessing and development is a plus
• Experience with cell line development is a plus
• Continuous strong focus on meeting or exceeding expectations in executing deliverables, performance and results.
• Ability to track and measure performance against defined metrics.
• Self-starter with high degree of energy, independence, initiative, and self-motivation, as illustrated by the ability to instill a sense of pace and urgency into the team.
• Someone who moves fast and decisively in a balanced manner, with a passion for the growing company.
• Passionate, collaborative, creative, willing to take prudent risks, and motivated by the creation of a company focused on transformative treatments for patients and their families.
Job Details:
• Direct Hire
• Monday-Friday, day shift
• Salary dependent upon level of education and experience
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As part of our promise to talent, Kelly supports those who work with us through a variety of benefits, perks, and work-related resources. Kelly offers eligible employees voluntary benefit plans including medical, dental, vision, telemedicine, term life, whole life, accident insurance, critical illness, a legal plan, and short-term disability. As a Kelly employee, you will have access to a retirement savings plan, service bonus and holiday pay plans (earn up to eight paid holidays per benefit year), and a transit spending account. In addition, employees are entitled to earn paid sick leave under the applicable state or local plan. Click here for more information on benefits and perks that may be available to you as a member of the Kelly Talent Community.
Why Kelly® Science & Clinical?
Kelly Science & Clinical is your connection to premier scientific and clinical companies looking to hire industry experts just like you. Our team creates expert talent solutions to solve the world's most critical challenges. Every day, we match science professionals with dream jobs that fit their skills, interests, and career goals—it's the way we think job searching should be. Nearly 100 percent of our science recruiters have a professional background and education in science, so we know a thing or two about the science market and how to get your expertise noticed.About Kelly
Work changes everything. And at Kelly, we're obsessed with where it can take you. To us, it's about more than simply accepting your next job opportunity. It's the fuel that powers every next step of your life. It's the ripple effect that changes and improves everything for your family, your community, and the world. Which is why, here at Kelly, we are dedicated to providing you with limitless opportunities to enrich your life—just ask the 300,000 people we employ each year.Kelly Services is proud to be an Equal Employment Opportunity and Affirmative Action employer. We welcome, value, and embrace diversity at all levels and are committed to building a team that is inclusive of a variety of backgrounds, communities, perspectives, and abilities. At Kelly, we believe that the more inclusive we are, the better services we can provide. Requests for accommodation related to our application process can be directed to Kelly's Human Resource Knowledge Center. Kelly complies with the requirements of California's state and local Fair Chance laws. A conviction does not automatically bar individuals from employment. Kelly participates in E-Verify and will provide the federal government with your Form I-9 information to confirm that you are authorized to work in the U.S.
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